Selective Adsorption Performance of Graphene Oxide Toward Norfloxacin and Moxifloxacin in Aqueous Solution

Authors

  • Amri Amri Research Center of Inorganic Materials and Coordination Complexes, Universitas Sriwijaya, Palembang, 30139, Indonesia
  • Alfan Wijaya Research Center of Inorganic Materials and Coordination Complexes, Universitas Sriwijaya, Palembang, 30139, Indonesia

DOI:

https://doi.org/10.26554/ijmr.20253372

Keywords:

Graphene Oxide, Selective Adsorption, Norfloxacin, Moxifloxacin

Abstract

Norfloxacin (NFX) and moxifloxacin (MFX) are widely used fluoroquinolone antibiotics that are frequently detected as residues in aquatic environments. Their persistent presence can increase the risk of antibiotic-resistant bacteria (ARB) emerging, making the selective removal of these compounds from water systems essential. This study evaluates the adsorption selectivity of NFX and MFX using graphene oxide (GO) as a potential adsorbent. The results show that GO exhibits a higher affinity for NFX than for MFX, indicating selective interactions between the functional groups of GO and NFX molecules. These findings confirm the potential of GO as a selective adsorbent for the removal of specific antibiotics from aqueous solutions and provide a basis for developing more effective wastewater treatment strategies.

References

Adawiyah, R., N. Yuliasari, Y. Hanifah, K. Alawiyah, and N. Rahayu Palapa (2024). Utilizing Areca catechu L. Fruit Peel-Derived Biochar and Hydrochar for Congo Red Adsorption: Kinetic and Thermodynamic Analysis. Indonesian Journal of Environmental Management and Sustainability, 8(4), 135–144.

Aditi and G. Jindal (2025). Conjugated Nanoparticles Based on Graphene Oxide for the Optical Sensing of Copper Ions and Chlorpyrifos in Edible Materials. Microchemical Journal, 218, 115670.

Akintayo, M., H. Long, H. Rong, F. Zhang, A. Kumar, A. Ndudi, B. Tafa, O. Ayodele, O. Princess, F. Nkinahamira, P. Ndagijimana, G. Mehboob, and D. Guo (2025). Impacts of Tetracycline–Lead Co-Contamination on Soil Ecosystem Functions and Remediation Using Green-Synthesized Iron–Graphene. Applied Soil Ecology, 216, 106533.

Amri, A. and Y. Hanifah (2023). Synthesis of Graphene Oxide Using Hummers Method as Adsorbent of Malachite Green Dye. Indonesian Journal of Material Research, 1(1), 29–34.

Amri, A., A. Lesbani, and R. Mohadi (2023). Malachite Green Dye Adsorption from Aqueous Solution Using a Ni/Al Layered Double Hydroxide–Graphene Oxide Composite Material. Science and Technology Indonesia, 8(2), 280–287.

Amri, A. and S. Wibiyan (2024). Selective Adsorption of Anionic Dyes by Graphene Oxide Adsorbent. Indonesian Journal of Material Research, 2(2), 47–50.

Berber, M. R., F. Rosa, and A. Iranzo (2021). Mechanically Robust and Highly Conductive Polymer Electrolyte Membranes Comprising High Molecular Weight Poly[2,2′-(bipyridyl)bibenzimidazole] and Graphene Oxide. Polymer, 233, 124223.

dos Santos, N. R., G. P. Gongora, J. S. de Sousa, M. E. C. Ferreira, R. Bergamasco, and L. F. Cusioli (2025). Application of Three-Dimensional Structures of Polylactic Acid (PLA) Impregnated with Graphene Oxide for Adsorption of Ibuprofen. Journal of Water Process Engineering, 78, 108672.

El-Aassar, M. R., H. M. A. Hassan, M. S. Alhumaimess, I. H. Alsohaimi, M. Alzaid, A. K. Alanazi, M. Algarni, S. Albarakati, and M. Aadil (2025). Synthesis of Nd/Ni Co-Doped LaFeO₃/g-C₃N₄ Heterostructures for Photocatalytic Norfloxacin Degradation. Inorganic Chemistry Communications, 182, 115478.

Li, H., S. Xu, C. Wang, F. Cheng, Y. Yi, W. Zhang, and H. Chen (2025). Bi/Co@α-MnO₂ Composite as an Oxidant-Free Catalyst for Norfloxacin Degradation: Mechanistic Insights and Environmental Compatibility. Journal of Water Process Engineering, 79, 109027.

Mahmoud, A., F. I. Abo El-Ela, R. Mahmoud, A. Z. Shehata, H. A. El-Raheem, E. Salama, A. A. Allam, H. E. Alfassam, and A. Zaher (2025). Eco-Friendly Moxifloxacin Removal Using Date Seed Waste and Ni–Fe LDH: Adsorption Efficiency and Antimicrobial Potential. Ecotoxicology and Environmental Safety, 297, 118256.

Ouyang, E., Z. Hu, J. Zhang, X. Huang, X. Jiang, R. Zhao, and H. Yang (2025). Structural Design of Functionalized Multilayer Magnetic Starch-Based Biosorbent and Its Efficient Adsorption of Moxifloxacin. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 725, 137583.

Pham, D. T., P. Chomchalao, K. Bunneramit, P. Kladcharoen, R. Khotcharrat, and W. Tiyaboonchai (2025). Development of Sustained-Release Extemporaneous Moxifloxacin Loaded Commercial Soft Hydrogel Contact Lenses. Heliyon, 11(3), e42436.

Podder, S., S. Dey, and A. Chatterjee (2025). Facile and Green Synthesis of Reduced Graphene Oxide Using Cajanus cajan Leaf Extract and Exploration of Potential Reducing Phytoconstituents Using Quantum Chemical Calculations. Next Materials, 9, 101221.

Prasetya, N. B. A., F. I. S. Masfufah, N. Ngadiwiyana, Y. Yassaroh, and R. Wulandari (2025). pH-Sensitive Chitosan/Graphene Oxide Films Enriched with Red Cabbage Anthocyanins for Visual Spoilage Detection in Chicken Meat. International Journal of Biological Macromolecules, 329, 147866.

Shabavi, Z. M., E. Shakerzadeh, T. Yadav, and E. C. Anota (2024). Quantum Chemical Insights into the Adsorption Performance of Pristine and M-Encapsulated (M = Li, Na, K) B₁₂N₁₂ Nanocages Toward Ciprofloxacin, Levofloxacin, Moxifloxacin, Delafloxacin and Ofloxacin Antibiotics. Diamond and Related Materials, 148, 111463.

Shaha, C. K., S. Saha, S. Karmaker, and T. K. Saha (2024). Efficient Removal of Moxifloxacin from Aqueous Solutions Using Sulfonated Graphene Oxide: Adsorption Mechanisms, Thermodynamics, and Reusability. Journal of Water Process Engineering, 67, 106187.

Sharma, P., A. Choudhary, V. C. Janu, A. Yadav, D. Patidar, and P. Vasistha (2025). Influence of Synthesis Parameters on Surface Area and Pore Structure of Reduced Graphene Oxide (rGO): Insight via QSDFT Analysis. Solid State Communications, 406, 116186.

Sun, S., T. Sun, D. Zhang, J. Liu, L. Ren, C. Chen, W. Yao, and Z. Shi (2026). Enhanced Photocatalytic Degradation of Norfloxacin via SPR Effect in CuNi/TiO₂–ₓ Composite under Visible Light. Journal of Photochemistry and Photobiology A: Chemistry, 471, 116710.

Sun, W., X. Liu, S. Gao, Y. Li, and H. Ji (2025). Starch Modified g-C₃N₄ Enhanced Adsorption and Photocatalytic Synergistic Removal of Norfloxacin under Simulated Solar Light. Chemical Engineering Journal, 524, 169032.

Vietanti, F., S. P. G., and Y.-J. Chou (2025). Initial Assessment of Nitrogen-Doped Reduced Graphene Oxide-Enhanced 76S Mesoporous Bioactive Glass: Structural, Mechanical, and Biological Analysis. Journal of Non-Crystalline Solids, 670, 123839.

Vinsiah, R., R. Mohadi, and A. Lesbani (2020). Performance of Graphite for Congo Red and Direct Orange Adsorption. Indonesian Journal of Environmental Management and Sustainability, 4(4), 125–132.

Widakdo, J., F. A. Priodani, H. F. M. Austria, T. Han-Huang, A. Rianjanu, C. S. Budi, A. Anawati, and W.-S. Hung (2025). Precision Engineered Graphene Oxide Membranes Optimizing Thin Film Composite Layers for Solvent and Dye Separation. Science and Technology Indonesia, 10(4), 1031–1048.

Yazidi, I., N. El Bardiji, Y. El Boundati, J. El Haskouri, K. Ziat, N. Allali, F. Sitel, and M. Chabbi (2025). Dual-Functional Hydrochar via Hydrothermal Carbonization for Norfloxacin Removal: Fractal Adsorption Kinetics and Mechanism Elucidation. Science of The Total Environment, 1000, 180405.

Yuan, L., P. Du, T. Wen, X. Zhao, X. Gao, B. Liu, H. Huang, C.-C. Wang, and D. Liu (2025). Sulfate-Grafted Metal–Organic Framework Derived from Sulfuric Acid Pickling Wastewater for Effective Adsorption of Moxifloxacin Antibiotic. Separation and Purification Technology, 376, 134100.

Zhang, Y., M. Yang, W. Cui, L.-J. Xu, D. Zhang, Y. Tao, J.-L. Han, and A. Wang (2025). Alleviating Moxifloxacin-Induced Biological Inhibition in Ethanol and Cl⁻ Coexisted Wastewater: Why UV/H₂O₂ is Better Than Fenton. Chemical Engineering Journal, 519, 165370.

Zhou, X., Z. Ding, Z. Li, X. Li, F. Meng, L. Lu, and L. Wang (2026). Adsorption Characteristics of Sludge-Based Composite Biochar for Norfloxacin and Oxytetracycline in a Binary System. Biochemical Engineering Journal, 225, 109949.

Zou, M., W. Tian, M. Chu, H. Gao, and D. Zhang (2022). Biochar Composite Derived from Cellulase Hydrolysis Apple Branch for Quinolone Antibiotics Enhanced Removal: Precursor Pyrolysis Performance, Functional Group Introduction and Adsorption Mechanisms. Environmental Pollution, 313, 120104.

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Published

2025-11-04

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